Overview

Familial renal disease is an uncommon cause of kidney failure in dogs and cats. Most causes are breed-related (familial) and some are inherited. Some are congenital (present at birth). Renal dysplasia is a type of familial kidney disease characterized by abnormal cellular differentiation of kidney tissue. Dogs and cats with kidney disease caused by these diseases have the typical symptoms of kidney failure, including weight loss, loss of appetite, depression, and increased water consumption and urination. A list of familial kidney diseases by dog and cat breeds is found below.

Educational information only. This page is general guidance and is not a substitute for professional veterinary advice. Never give medicines or change treatment without consulting a veterinarian. If your pet is unwell, contact OC Pets or seek emergency care.

Sources (reused under open licences, with thanks): Wikipedia — “Familial renal disease in animals” (CC BY-SA 4.0) · Compiled by OC Pets Veterinary Clinic, updated 15-06-2026.